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  • Title: [Relation between serum levels of C-terminal fragment, beta 2 microglobulin and creatinine in patients with chronic nephropathies at different stages of the disease].
    Author: Kowalski D, Starzyk J, Kowalska K.
    Journal: Wiad Lek; ; 42(19-21):1038-43. PubMed ID: 2700400.
    Abstract:
    The serum concentrations of the C-terminal fragment of parathyroid hormone, beta 2-microglobulin and creatinine were determined in 40 patients with chronic nephropathies at various stages of renal function impairment. Statistically significant positive correlations were found between the concentrations of creatinine and the C-terminal fragment (r = 0.6656, p less than 0.001), creatinine and beta 2-microglobulin (r = 0.7752, p less than 0.001) and beta 2-microglobulin and the C-terminal fragment (r = 0.6391, p less than 0.001). The authors believe that the concentration of the C-terminal fragment i the serum in chronic renal failure is not reflecting the degree of secondary hyperparathyroidism but is only an index of renal function failure.
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