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  • Title: [Clinical study on the treatment of dyskinesia by L-stepholidine].
    Author: Le W.
    Journal: Zhonghua Shen Jing Jing Shen Ke Za Zhi; 1989 Dec; 22(6):335-7, 381-2. PubMed ID: 2700694.
    Abstract:
    134 cases of dyskinesia caused by various CNS diseases were treated with a new type of DA blocker L-Stepholidine (1-SPD). Good response was obtained in 72% (29/40) of L-dopa induced abnormal involuntary movements in Parkinson disease, 79% (34/43) of Tourette syndrome, and 65% (15/23) of tardive dyskinesia through a short-term follow-up. No serious side effects were found within the therapeutic dosage of 50-225mg/day The results showed that L-SPD is a new type of anti-dyskinesia agent deserving further pharmacological investigation.
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