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  • Title: [THE ROLE OF NUTRITION IN THE GENESIS OF-HEPATIC OSTEODYSTROPHY IN PRIMARY BILIARY CIRRHOSIS].
    Author: Prashnova MK, Raikhelson KL, Ivanova OE, Nazarenko LI, Baranovsky AY.
    Journal: Eksp Klin Gastroenterol; 2015; (8):30-3. PubMed ID: 27017740.
    Abstract:
    THE PURPOSE: To evaluate the effect of diet on the development of hepatic osteodystrophy in patients with primary biliary cirrhosis. MATERIALS AND METHODS: In 24 women with PBC, including signs of autoimmune hepatitis (PBC/AIH)--9 persons and 19 women in the control group were analyzed the daily diet, body composition, as well as bone mineral density in the lumbar spine and femur by dual-energy X-ray adsorbtsiometrii (DEXA). THE RESULTS: In PBC incidence of osteoporosis and severe osteoporosis was 22.7% and 9.1%, respectively, and osteopenia--59.1%, with a lesion predominantly lumbar spine. Inadequate intake of calcium in patients with PBC is associated with lower density of the femur. The high protein content in the diet has a protective effect on bone mineral density, associating with the development of osteopenia.
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