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  • Title: Effectiveness of Intraductal Meibomian Gland Probing for Obstructive Meibomian Gland Dysfunction.
    Author: Sik Sarman Z, Cucen B, Yuksel N, Cengiz A, Caglar Y.
    Journal: Cornea; 2016 Jun; 35(6):721-4. PubMed ID: 27032021.
    Abstract:
    PURPOSE: To evaluate the short-term effectiveness of intraductal meibomian gland probing using modified Maskin cannulas in patients with obstructive meibomian gland dysfunction. METHODS: The study prospectively included 58 eyes of 30 patients with a diagnosis of meibomian gland dysfunction who were refractory to medical treatment for at least 6 months. The patients were divided into 4 groups according to the number of probing procedures applied. During probing, sterile modified Maskin probes 2, 2.5, 4, and 6 mm in length were used. A tarsal massage was recommended after medical treatment. Preoperatively, then postoperatively at 1 week, 1 month, and 3 months, the Schirmer 1 test was performed, tear break-up time was measured, and images of the anterior segment were recorded. In addition, the Ocular Surface Disease Index questionnaire was completed at baseline and at 3 months. RESULTS: In all groups, there were no statistically significant differences between Schirmer 1 test results at preoperative and postoperative 3 months, but tear break-up time values measured at baseline and at 3 months differed significantly (5 seconds, 13 seconds, P < 0.001). In the analyses of anterior segment photographs of all patients, statistically significant postprocedural decreases in conjunctival hyperemia (P < 0.0001) and eyelid margin vascularization (P = 0.004) were detected, and the later Ocular Surface Disease Index scores showed a significant improvement between preop and 3 months. CONCLUSIONS: A procedure using modified Maskin probes was effective and reliable in the short term for patients with meibomian gland dysfunction.
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