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  • Title: New test for endothelin receptor type B (EDNRB) mutation genotyping in horses.
    Author: Ayala-Valdovinos MA, Galindo-García J, Sánchez-Chiprés D, Duifhuis-Rivera T.
    Journal: Mol Cell Probes; 2016 Jun; 30(3):182-4. PubMed ID: 27039359.
    Abstract:
    Lethal white foal syndrome (LWFS) is an autosomal recessive disease of neonatal foals characterized by a white hair coat and a functional intestinal obstruction. Traditional techniques for identifying the dinucleotide mutation (TC→AG) of the endothelin receptor B gene (EDNRB) associated with LWFS are time-consuming. We developed a new technique based on mutagenically separated polymerase chain reaction (MS-PCR) for simple detection of the EDNRB genotype in horses.
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