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  • Title: The Rapid Effectiveness of Minocycline against Scrub Typhus Meningoencephalitis.
    Author: Naoi T, Shimazaki H, Sawada M.
    Journal: Intern Med; 2016; 55(7):805-9. PubMed ID: 27041169.
    Abstract:
    Scrub typhus is associated with various clinical symptoms. However, the pathogenesis of scrub typhus infection remains to be elucidated. A 73-year-old man was admitted to our hospital with consciousness disturbance and suspected meningoencephalitis. The patient's laboratory data showed deterioration and were indicative of hemophagocytic lymphohistiocytosis (HLH). A whole body examination to detect the trigger disease revealed an eschar, which is a characteristic of scrub typhus, on his back. His symptoms showed dramatic improvement after the administration of minocycline (MINO). This case report highlights that the clinical course of a case of scrub typhus meningoencephalitis that was cured with MINO.
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