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  • Title: An ultrasensitive and incubation-free electrochemical immunosensor using a gold-nanocatalyst label mediating outer-sphere-reaction-philic and inner-sphere-reaction-philic species.
    Author: Fang CS, Oh KH, Oh A, Lee K, Park S, Kim S, Park JK, Yang H.
    Journal: Chem Commun (Camb); 2016 Apr 30; 52(34):5884-7. PubMed ID: 27052458.
    Abstract:
    This communication reports a new nanocatalytic scheme based on the facts that the redox reaction between a highly outer-sphere-reaction-philic (OSR-philic) species and a highly inner-sphere-reaction-philic (ISR-philic) species is slow and that an OSR- and ISR-philic Au-nanocatalyst label can mediate the two different types of redox species. This scheme allows highly sensitive and incubation free detection of creatine kinase-MB.
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