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  • Title: Population variation of HLA genes in rural communities in Brazil, the Quilombos from the Vale do Ribeira, São Paulo - Brazil.
    Author: Nunes K, Piovezan B, Torres MA, Pontes GN, Kimura L, Carnavalli JE, Mingroni Netto RC, Moraes ME, Meyer D.
    Journal: Hum Immunol; 2016 Jun; 77(6):447-8. PubMed ID: 27060779.
    Abstract:
    In the present study, we characterized the allelic and haplotypic profile of the genes HLA-A, -B, -C and -DRB1 (PCR-SBT) in a population sample of 144 highly admixed individuals, coming from rural communities in Brazil (Quilombos from Vale do Ribeira, in the State of São Paulo). Furthermore, we identified three individuals with a new null allele in the HLA-C gene (HLA-C(∗)02:105N), associated with the haplotype HLA-A(∗)80: 01∼B(∗)18: 01:01G∼DRB1(∗) 07:01.
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