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  • Title: [Effect of the stimulation of lymphocyte adrenoreceptors on antitumor immunity in vitro].
    Author: Kharkevich DD, Kadagizde ZG.
    Journal: Farmakol Toksikol; 1989; 52(1):61-4. PubMed ID: 2707425.
    Abstract:
    It was found that the stimulating effect of alpha-adrenomimetic mesatone in the test of lymphocyte adhesion inhibition in patients with rectum cancer in vitro was eliminated by beta-adrenergic blocker phentolamine and the inhibitory effect of beta-adrenergic antagonist propranolol. It was shown in vitro that lymphocyte chemoreceptor sensitivity to the stimulating effect of mesatone decreased and sensitivity to the inhibitory effect of isadrine increased in patients with advanced stages of rectum cancer.
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