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Title: Deglycosylation of the chymotryptic collagen-binding fragment of human plasma fibronectin does not modify its affinity to denatured collagen. Author: Delannoy P, Montreuil J. Journal: FEBS Lett; 1989 Apr 10; 247(1):25-7. PubMed ID: 2707448. Abstract: N-Glycanase deglycosylation of purified 44 kDa chymotryptic collagen-binding domain from human plasma fibronectin does not significantly modify its behavior on gelatin affinity chromatography. This indicates that carbohydrates do not play any role in the binding affinity of fibronectin to collagen. The influence of changes in glycosylation on the biological functions of fibronectin is discussed.[Abstract] [Full Text] [Related] [New Search]