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  • Title: Healing of necrobiotic ulcers with antiplatelet therapy. Correlation with plasma thromboxane levels.
    Author: Heng MC, Song MK, Heng MK.
    Journal: Int J Dermatol; 1989 Apr; 28(3):195-7. PubMed ID: 2707946.
    Abstract:
    Necrobiosis lipoidica in diabetics has been considered to be a cutaneous manifestation of diabetic microangiopathy. Seven diabetic patients with necrobiotic ulcers of recent onset that healed after administration of acetylsalicylic acid and dipyridamole had elevated thromboxane levels. Healing was associated with depression of the elevated thromboxane levels in all seven patients.
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