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  • Title: New streptophenazines from marine Streptomyces sp. 182SMLY.
    Author: Liang Y, Chen L, Ye X, Anjum K, Lian XY, Zhang Z.
    Journal: Nat Prod Res; 2017 Feb; 31(4):411-417. PubMed ID: 27097765.
    Abstract:
    Six phenazines including three new ones were isolated from the culture of a marine actinomycete Streptomyces sp. 182SMLY. Based on the analyses of NMR, HRESIMS, optical rotation value, and CD data, the structures of these isolated compounds were determined as new phenazines of (-)-streptophenazines M-O and known phenazines of 1-carbomethoxyphenazine and (-)-streptophenazines A and B. (-)-Streptophenazine B showed activity in suppressing the growth of methicillin-resistant Staphylococcus aureus with MIC value of 4.2 μg/mL.
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