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  • Title: [Determination of free erythrocyte protoporphyrin in thalassemic trait].
    Author: Vayá A, Mira Y, Miralles F, Aznar J.
    Journal: Sangre (Barc); 1989 Feb; 34(1):47-9. PubMed ID: 2711285.
    Abstract:
    Free erythrocyte protoporphirin (FEP), along with diverse haematologic and iron metabolism data, were determined in 60 carriers of the thalassaemic trait (29 beta and 31 delta beta). FEP rates were significantly higher in thalassaemia carriers (39.04 +/- 14.12 micrograms/dl) than in a control group (24.95 +/- 4.70 micrograms/dl) (p less than 0.05). No correlation between FEP and any other iron metabolism parameter, or the severity of anaemia, was found. No FEP differences appeared between the beta (41.06 +/- 16.5 micrograms/dl) and delta beta (37.1 +/- 11.06 micrograms/dl) traits, so, although FEP rates are increased in thalassaemia carriers, they are useless in differentiating between the commonest thalassaemic forms in our country.
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