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  • Title: Differences in Urodynamic Parameters Between Women With Interstitial Cystitis and/or Bladder Pain Syndrome and Severe Overactive Bladder.
    Author: Shim JS, Kang SG, Park JY, Bae JH, Kang SH, Park HS, Moon du G, Cheon J, Lee JG, Kim JJ, Oh MM.
    Journal: Urology; 2016 Aug; 94():64-9. PubMed ID: 27130264.
    Abstract:
    OBJECTIVE: To identify differences in urodynamic parameters between female outpatients with interstitial cystitis (IC) and/or bladder pain syndrome (BPS) and severe overactive bladder (OAB). MATERIALS AND METHODS: This cross-sectional study included 24 and 28 consecutive IC/BPS and severe OAB female patients, respectively. IC/BPS was defined based on the American Urological Association guideline, and severe OAB was defined based on baseline symptoms recorded in a voiding diary. Before treatment, symptom assessment using questionnaires and a 3-day voiding diary, as well as laboratory tests, were performed at the initial visit. The patients' baseline characteristics and urodynamic parameters were compared between the IC/BPS and severe OAB groups. RESULTS: The IC/BPS group showed fewer episodes of urge incontinence and shorter duration of symptoms than the severe OAB group (P = .019, P = .017, respectively). Volumes at first sense, normal desire, strong desire, and maximal capacity during filling cystometry (MBC) were significantly higher in the severe OAB group than in the IC/BPS group (P <.001, P <.001, P = .006, P <.001, respectively). The IC/BPS and severe OAB groups showed significant differences in urodynamic parameters in terms of MBC and the volume discrepancy between MBC and maximal voided volume (P <.001, both). The receiver operating characteristic curve also showed an area under the curve of 0.760 and 0.783 for MBC and volume discrepancy, respectively (both P <.001). CONCLUSION: Data from our study suggest that combined with other clinical findings, urodynamic studies could provide useful information to differentiate between a diagnosis of IC/BPS or severe OAB.
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