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  • Title: Aluminum-induced granulomas in a tattoo.
    Author: McFadden N, Lyberg T, Hensten-Pettersen A.
    Journal: J Am Acad Dermatol; 1989 May; 20(5 Pt 2):903-8. PubMed ID: 2715443.
    Abstract:
    A patient who developed localized, granulomatous reactions in a tattoo is described. With the use of scanning electron microscopy and energy dispersive x-ray microanalysis, both aluminum and titanium particles were found in the involved skin sections. Intradermal provocation testing with separate suspensions of aluminum and titanium induced a positive response only in the case of aluminum. Examination by scanning electron microscopy and energy dispersive x-ray microanalysis of the provoked response established aluminum as the only nonorganic element present in the test site tissue. This is the first report of confirmed aluminum-induced, delayed-hypersensitivity granulomas in a tattoo.
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