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  • Title: [Carcinoma of the kidney as a complication of acquired cystic disease of the kidney in patients subjected to treatment with periodical hemodialysis].
    Author: Almirall J, Mallofrè C, Campistol JM, Montoliu J, Andreu J, Ribalta T.
    Journal: Med Clin (Barc); 1989 Mar 11; 92(9):341-3. PubMed ID: 2716429.
    Abstract:
    Three cases of acquired cystic renal disease (ACRE) are reported in patients treated with periodical hemodialysis (HD) who developed neoplastic degeneration. In the first patient, diagnosis was a chance finding of nephrectomy during renal transplantation. The second patient was discovered following hematuria, and in the third patient disseminated metastases were the presenting feature of the disease. The finding of renal tumours associated with ACRE is a well known fact; however, metastatic disease has been infrequently reported. Generally, the denomination "adenoma" is adopted for tumours with a maximal diameter shorter than 3 cm, as they seldom develop metastases. However, the third patient had an adenocarcinoma measuring 2 cm in diameter. One of the parameters that best correlates the occurrence of ACRE and tumour development is the duration of HD; therefore, it is suggested that those patients who have received substitution therapy for longer than 3 years should undergo radiological studies for the early identification of these complications.
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