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  • Title: A New Iridoid from the Aerial Parts of Hedyotis pilulifera.
    Author: Hoai NT, Duc HV, Phu ND, Kodama T, Itob T, Morita H.
    Journal: Nat Prod Commun; 2016 Mar; 11(3):365-7. PubMed ID: 27169182.
    Abstract:
    A new iridoid, 10-acetylborreriagenin (1), and five known iridoid glycosides (2-6), were isolated from the aerial parts of Hedyotis pilulifera. Their structures were elucidated by spectral analyses, including 1D- and 2D-NMR, and HR-ESI-MS, and comparisons with the NMR data reported in the literature. The isolated compounds 1-6 were tested against six bacterial species. Among them, 10-acetylborreriagenin (1) showed antibacterial activity against Staphylococcus aureus, with an MIC value of 100 µg/mL.
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