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  • Title: Isolation and Quantification of Pinitol, a Bioactive Cyclitol, in Retama spp.
    Author: González-Mauraza NH, León-González AJ, Espartero JL, Gallego-Fernández JB, Sánchez-Hidalgo M, Martin-Cordero C.
    Journal: Nat Prod Commun; 2016 Mar; 11(3):405-6. PubMed ID: 27169192.
    Abstract:
    The genus Retama (Fabaceae) is widely distributed in the Mediterranean region. In the present study, pinitol (3-O-methyl-chiro-inositol), an anti-inflammatory and antidiabetic molecule, was isolated from aerial parts of R. monosperma, and its structure established on the basis of spectroscopic techniques (1D/2D NMR) and MS. Identification and quantification of pinitol in R. raetam and R. sphaerocarpa were also performed. R. monosperma had the highest concentration of pinitol (2.3%). The presence of pinitol in aqueous extracts of Retama spp. may explain the adaptation of these plants to drought and salinity. Furthermore, pinitol could be considered as a mediator in the anti-inflammatory and hypoglycemic activities of Retama spp., which are traditionally used to treat diabetes.
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