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  • Title: Blood coagulation changes in rats during development of epithelioma.
    Author: Tomasiuk R, Gawlowska H, Sawicka B, Mielicki W, Wierzbicki R.
    Journal: Neoplasma; 1989; 36(2):179-84. PubMed ID: 2716922.
    Abstract:
    Coagulation activity in the blood of rats during the development of Guerin epithelioma was studied. Clotting time, level of fibrinogen and some coagulation factors (II, V, VII + X) in the plasma were determined and thromboelastographic studies were performed. Two periods of blood hypercoagulability were observed in the process of epithelioma development. The first a short-term period, was noticed during the first days following the implantation of the neoplastic tissue. The second took place during the intensive growth of the primary tumor and metastases.
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