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  • Title: [Calcium and citrate excretion by patients with calculi and healthy probands during induced acidosis].
    Author: Bothor C, Berg W, Donner M, Pirlich W.
    Journal: Urologe A; 1989 Mar; 28(2):112-5. PubMed ID: 2718293.
    Abstract:
    Acidosis induced increase in renal calcium excretion and decrease in renal citrate excretion was produced by means of ammonium chloride load in 15 patients with recurrent oxalate lithiasis and in 15 control subjects. The expected increase in the calcium citrate relationship in urine is more marked and more lasting in stone patients. Stone formers obviously respond to an acidotic metabolic situation by a more clear relative decrease in citrate excretion, in addition to more intensive calcium excretion, which is known. A certain individual sensitivity of renal tubular mechanisms is discussed with regard to acid base changes.
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