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  • Title: [Pulmonary function tests in asthmatic children in treatment with tulobuterol].
    Author: Pérez-Martini L, Blanco RA, Heffner G, Ordóñez-Comparini R.
    Journal: Bol Med Hosp Infant Mex; 1989 Apr; 46(4):241-5. PubMed ID: 2719810.
    Abstract:
    The objective of the present study was to evaluate the effectiveness and tolerance of a new beta-2 agonist, tulobuterol, in children. Fifteen patients with acute asthma were studied, during a period of 21 days. Significant increase in forced vital capacity (FVC), forced expiratory volume in the first second (FEV-1), and forced expiratory flow 25-75% (FEF 25-75%) were observed after treatment with tulobuterol (p less than 0.01). Clinical improvement was evident as measured by a clinical-scale and a functional scale. The only side effect attributable to the drug was a tremor which was observed in three patients.
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