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  • Title: Electrophysiological identification of spinally projecting neurons in the lateral reticular nucleus of the rat.
    Author: Liu RH, Tang JS, Hou ZL.
    Journal: Brain Res; 1989 Mar 06; 481(2):350-5. PubMed ID: 2720387.
    Abstract:
    Eighty-four neurons in the caudal ventrolateral medullary reticular formation were antidromically activated by the stimulation of the dorsolateral funiculus in 49 urethane-anesthetized rats. Of 76 neurons, 37 had no spontaneous discharge. Of the neurons that had spontaneous discharges, 80% had firing rates between 0.1 and 15 Hz. The average conduction velocity, determined among 70 neurons, was 15.20 +/- 1.23 m/s, and 87% had conduction velocities within the range of 2-30 m/s. This study further confirms the existence of spinally-projecting neurons in the lateral reticular nucleus (LRN) of the caudal medulla, and some of them are probably responsible for the descending controls of nociception from the LRN.
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