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  • Title: Acetylator phenotype in psoriasis.
    Author: Jiménez-Nieto LC, Ladero JM, Fernández-Gundín MJ, Robledo A.
    Journal: Dermatologica; 1989; 178(3):136-7. PubMed ID: 2721804.
    Abstract:
    Acetylator phenotype has been determined with sulfamethazine in 64 psoriatic patients and in 157 normal control subjects. Forty patients (62.5%) versus 90 control subjects (57.3%) were slow acetylators (p = NS). However, 81% of the 27 patients with psoriatic siblings were slow acetylators (p less than 0.05). Slow acetylator phenotype may be a genetic risk factor for the development of psoriasis.
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