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Pubmed for Handhelds

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  • Title: Ophthalmic Complications Related to Chemotherapy in Medically Complex Patients.
    Author: Harman LE.
    Journal: Cancer Control; 2016 Apr; 23(2):150-6. PubMed ID: 27218792.
    Abstract:
    BACKGROUND: Systemic cancer therapies cause a variety of ophthalmic complications. Mitigating harmful adverse events involves screening patients at risk for ocular injury and vision loss. METHODS: A review of the relevant literature on the ophthalmic complications of cancer therapy was used to formulate an approach to screening patients for serious complications presenting at a nonophthalmic specialty center. RESULTS: Rarely, ocular complications of cancer therapy can occur. Establishing a causal association for any given agent is complicated because many treatment-related adverse events result in symptoms and ocular findings indistinguishable from primary eye disorders. CONCLUSIONS: Recognizing potentially serious ocular complications of cancer therapy before they result in irreversible injury starts with taking a relevant clinical history and performing a basic eye examination, including assessments of visual acuity and fields. Given the wide range of treatment-related adverse events and the challenges of diagnosis, the screening process plays an important role in expediting referral to an ophthalmologic specialist.
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