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  • Title: [Spermatozoal antibodies in cervical mucus and in the luminal fluid of the uterus in sterile patients].
    Author: Maas DH, Timm G, Mesrogli M, Degenhardt F.
    Journal: Geburtshilfe Frauenheilkd; 1989 Mar; 49(3):248-51. PubMed ID: 2721885.
    Abstract:
    Poor postcoital tests in infertile patients may be due to dysmucurrhoea, low sperm count, or specific antibodies against spermatozoa. Using a latex agglutination test ("Sperm-antibody-slide-test", Fa. Biotec, Hannover), we examined the cervical and uterine secretions of the patients for sperm antibodies. The results showed a close correlation between a positive sperm-antibody-test and a poor postcoital test, especially in those couples with regular sperm quality. Also in cases with normal postcoital tests, positive sperm-antibody titers can be observed. Therefore, the sperm-antibodies may disturb fertilization in infertile patients even without causing immobilization or agglutination of the spermatozoa in the female genital tract fluids. The determination of the spermatozoa-antibody content in the cervical and uterine secretions must be regarded as an improvement in the diagnostic procedure in human infertility.
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