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Title: Bilateral colobomas in a horse. Author: Schuh JC. Journal: J Comp Pathol; 1989 Apr; 100(3):331-5. PubMed ID: 2723162. Abstract: Bilateral true colobomas with retrobulbar cysts located over the optic nerves are described in an 8-year-old Quarterhorse mare with a history of progressive blindness. Colobomas result from the failure of an embryonic fissure to close and retrobulbar cysts result from eversion of the neuroectoderm through the colobomas. It could not be determined whether the small optic nerves and the scars, rosettes and disorganization of the cell layers in the retina were the result of concurrent dysplasia or were secondary to degeneration.[Abstract] [Full Text] [Related] [New Search]