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  • Title: [Noonan's syndrome associated with cardiovascular anomalies; report of three cases].
    Author: Yamauchi T, Morishita Y, Shimokawa S, Hashiguchi M, Yuda T, Taira A, Maruko O.
    Journal: Kyobu Geka; 1989 Jan; 42(1):32-4. PubMed ID: 2724730.
    Abstract:
    Noonan's syndrome has a phenotype similar to Turner's syndrome, but has no chromosome abnormalities. This syndrome is frequently associated with congenital heart diseases, particularly valvular pulmonary stenosis. Three patients of Noonan's syndrome with congenital heart disease were successfully operated upon. Diagnostic criteria, frequency of anomalies and the association of cardiac malformations have been discussed together with special surgical points of view.
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