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  • Title: Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells.
    Author: Tsai SF, Martin DI, Zon LI, D'Andrea AD, Wong GG, Orkin SH.
    Journal: Nature; 1989 Jun 08; 339(6224):446-51. PubMed ID: 2725678.
    Abstract:
    Genes expressed in erythroid cells contain binding sites for a cell-specific factor believed to be an important regulator for this haematopoietic lineage. Using high-level transient expression in mammalian cells, we have identified complementary DNA encoding the murine protein. The factor, a new member of the zinc-finger family of DNA-binding proteins, is restricted to erythroid cells at the level of RNA expression and is closely homologous between mouse and man.
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