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  • Title: Ultrastructure of Cardiomyocytes and Blood Capillary Endotheliocytes in the Myocardium under Conditions of Experimental Mechanical Injury to the Heart.
    Author: Novoselov VP, Savchenko SV, Porvin AN, Koshlyak DA, Nadev AP, Ageeva TA, Chikinev YV, Polyakevich AS.
    Journal: Bull Exp Biol Med; 2016 May; 161(1):134-6. PubMed ID: 27259494.
    Abstract:
    We studied ultrastructural changes in cardiomyocytes and blood capillary endotheliocytes in the ventricular myocardium in response to mechanical injury of the heart of varying severity in Wistar rats. Acute alterative changes in cardiomyocyte and endotheliocyte ultrastructure indicate impairment of the energy-producing, contractile, and protein-synthesizing functions of the cells after mechanical injury. These disorders play the key role in the development of acute contractile insufficiency of the myocardium in mechanical injury to the heart.
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