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  • Title: An alternative route to the arylvinyltriazole nucleosides.
    Author: Chudinov MV, Prutkov AN, Matveev AV, Grebenkina LE, Konstantinova ID, Berezovskaya YV.
    Journal: Bioorg Med Chem Lett; 2016 Jul 15; 26(14):3223-3225. PubMed ID: 27262598.
    Abstract:
    A new pathway to synthesis of arylvinyl ribavirin analogues is developed which makes it possible to obtain not only trans- but also cis-isomers at vinyl bond. By this route eight ribavirin 5-arylvinyl analogues are synthesized and their antiviral activity is evaluated.
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