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  • Title: Effect of copper sulphate on the antioxidant parameters in the rainbow trout fry, Oncorhynchus mykiss.
    Author: Yonar ME, Ispir U, Mişe Yonar S, Kirici M.
    Journal: Cell Mol Biol (Noisy-le-grand); 2016 May 30; 62(6):55-8. PubMed ID: 27262803.
    Abstract:
    The aim of this study was to evaluate antioxidant responses of rainbow trout (Oncorhynchus mykiss) exposed to different concentrations of copper sulphate (CuSO4). Fish were exposed to 0 (Group I-control), 5 (Group II), 15 (Group III) and 30 µg/L (Group IV) concentrations of CuSO4 for 14 days. Liver and gills samples were collected at the end of the experiment, and analysed for their oxidant-antioxidant status, including the malondialdehyde (MDA) level, the catalase (CAT) and glutathione peroxidase (GSH-Px) activities as well as the reduced glutathione (GSH) concentration. Results obtained showed that the levels of MDA increased in tissues of fish. Compared to control, GSH level and GSH-Px and CAT activities were significantly reduced in the fish that were exposed to different concentrations of CuSO4. The result demonstrated that CuSO4 has an oxidative-stress-inducing potential in fish.
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