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  • Title: Geometric packing constraints in egg phosphatidylcholine vesicles.
    Author: Huang C, Mason JT.
    Journal: Proc Natl Acad Sci U S A; 1978 Jan; 75(1):308-10. PubMed ID: 272647.
    Abstract:
    This investigation presents a quantitative analysis of the asymmetric transmembrane lipid packing geometry in egg phosphatidylcholine vesicles. The analysis uses hydrodynamic and nuclear magnetic resonance data obtained for homogeneous egg phosphatidylcholine vesicles and demonstrates that the average area per lipid head group and effective length of the lipid are greater on the outer monolayer than on the inner monolayer of the egg phosphatidylcholine vesicle. Results also indicate that the bilayer of the egg phosphatidylcholine vesicles has an asymmetrical interface through its center.
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