These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: QSAR analysis of acetylcholinesterase inhibitors by use of structure similarity methods.
    Author: Jerman-Blazic B, Fabic-Petrac I, Pecar S, Stalc A.
    Journal: Prog Clin Biol Res; 1989; 291():213-6. PubMed ID: 2726849.
    Abstract:
    QSAR analysis of acetylcholinesterase inhibitors by a computer system for classification of chemical compounds by use of structure similarity methods has shown that the activity of these compounds is highly correlated with the geometry and the shape of attached radicals. Best values of the biochemical properties were obtained for compounds containing an optimal length of the attached radicals R1 and R2. The predicted values of the bimolecular rate constant for four compounds agree very well with the experimental results.
    [Abstract] [Full Text] [Related] [New Search]