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  • Title: Sesquiterpenes from Inula japonica with Inhibitory Effects on Nitric Oxide Production in Murine Macrophage RAW 264.7 Cells.
    Author: Jin Q, Lee JW, Jang H, Choi JE, Lee D, Hong JT, Kim Y, Lee MK, Hwang BY.
    Journal: J Nat Prod; 2016 Jun 24; 79(6):1548-53. PubMed ID: 27276091.
    Abstract:
    Eight new sesquiterpenes (1-8), along with seven known sesquiterpenes (9-15), were isolated from a methanol extract of the flowers of Inula japonica. Their structures were elucidated by a combination of 1D and 2D NMR spectroscopic and HRESIMS data. All of isolates were evaluated for their inhibitory effects on nitric oxide production in LPS-induced RAW 264.7 cells, with their IC50 values ranging from 1.9 to 15.4 μM.
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