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  • Title: Sickle cell anemia and mitral valve replacement. Case report.
    Author: Bomfim V, Ribeiro A, Gouvea F, Pereira J, Björk V.
    Journal: Scand J Thorac Cardiovasc Surg; 1989; 23(1):75-7. PubMed ID: 2727649.
    Abstract:
    An 8-year-old black boy with sickle cell disease and severe hemolytic anemia crisis (95% hemoglobin S) also had mitral incompetence due to rheumatic valve disease. A 27 mm monostrut Björk-Shiley valve prosthesis was implanted after partial exchange transfusions had reduced the hemoglobin S to less than 40%. High-flow normothermic perfusion was used during extracorporeal circulation, with care taken to avoid hypoxia and acidosis. Postoperative recovery was uneventful.
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