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  • Title: [Status of humoral defense mechanisms of the middle ear in young children with acute suppurative otitis media].
    Author: Merkulova EP, Prozorovskaia KN, Babaian SS, Lialikova GV.
    Journal: Vestn Otorinolaringol; 1989; (2):51-4. PubMed ID: 2728180.
    Abstract:
    The concentration of lysozyme and immunoglobulins was measured in serum and middle ear secretion of young children suffering from acute suppurative otitis. It was found that the local synthesis of lysozyme increased. The high concentration of lysozyme and low concentration of immunoglobulins of all classes in the middle ear secretion of children aged up to three years can be associated with an immature local humoral immune response.
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