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  • Title: [Neutrophil granulocyte function in patients with malignant neoplasms].
    Author: Cherdyntseva NV, Bogdashin IV, Nebera SA, Vasil'ev NV.
    Journal: Vopr Onkol; 1989; 35(4):429-33. PubMed ID: 2728383.
    Abstract:
    The paper discusses the status of polymorphonuclear neutrophils (PMN) in untreated patients with stage III and IV lung and stomach cancer. Pronounced increase in peripheral blood neutrophil count was matched by decrease in the level of leukocyte cationic proteins. In vitro cytotoxic activity of PMN against K-562 cells was significantly higher in cancer patients, as compared to healthy controls, and unaccompanied by reaction of neutrophils to stimuli. NBT-test value variation range appeared wider in cancer patients than in controls.
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