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  • Title: [Investigation of intracavernous injection of papaverine for erectile impotence].
    Author: Takimoto Y, Kawazoe K, Hosokawa H, Hamada T, Ono M, Aoki Y, Yasuoka S.
    Journal: Hinyokika Kiyo; 1989 Jan; 35(1):71-6. PubMed ID: 2729023.
    Abstract:
    Forty milligrams papaverine HCl was intracavernously injected to 28 patients with erectile dysfunction for diagnosis and treatment in 14 cases in which it was injected a few times. We designed a brief manual method for measurement of penile hardness by artificial erection. Twenty of the patients corresponding to 71.4%, reacted, but only 16 (57.1%) had efficient erection for possibility of coitus. It was useful for the diagnosis of vascular dysfunction with dorsal penile arterial pulse sound examination in impotence. It was useful for the cases of small vascular impediment with preservation of nerve supply after the operation of intrapelvic malignancies, and self injection might be possible, but on the other hand, it had no effect for the patients of advanced age with vascular impediment and diabetes mellitus neuropathy, and with arteriosclerosis.
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