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  • Title: Cassane diterpenes with oxygen bridge from the seeds of Caesalpinia sappan.
    Author: Xu X, Yuan J, Zhou X, Li W, Zhu N, Wu H, Li P, Sun Z, Yang J, Ma G.
    Journal: Fitoterapia; 2016 Jul; 112():205-10. PubMed ID: 27316975.
    Abstract:
    The seeds of the medicinal plant Caesalpinia sappan yielded fourteen cassane-type diterpenes, including six new rearranged ones named as caesalppans A-F (1-6). Their structures were elucidated by spectroscopic analysis and comparison with literature data. The isolated new compounds 1-6 possess lactone-type cassane diterpenoid skeleton with an oxygen bridge between C-19 and C-20, and were tested cytotoxic activity against four cancer cell lines using the MTT method.
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