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Title: [Chemical Constituents of Cynanchum auriculatum]. Author: He JB, Jia J, Gou HP, Zhang XM, Miao XS, He F, Tao J. Journal: Zhong Yao Cai; 2015 Nov; 38(11):2318-20. PubMed ID: 27356383. Abstract: OBJECTIVE: To study the chemical constituents of Cynanchum auriculatum. METHODS: Nine compounds were isolated by silica gel, RP-18 column chromatography and Sephadex LH20. RESULTS: Nine compounds were isolated from the ethanol extract of Cynanchum auriculatum. Their structures were determined as sarcosin-3-O-β-cymaropyranoside (1), cynotophylloside B (2), clemaphenol A (3), deacetylmetaplexigenin (4), methyl-2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl- (1 --> 4) -6-deoxy-3-O-methyl-α-L-ribo-hexopyranoside (5), trans-p-hydroxy cinnamic methyl ester (6), cyclo(D-Pro-D-Leu) (7), 3α-hydroxy-5α ,6α-epoxy-7-megastigmen9-one (8) and ferulic acid methyl ester (9) on the basis of spectral analysis. CONCLUSION: Compounds 3, 5 and 6 - 9 are isolated from Cynanchum auriculatum for the first time.[Abstract] [Full Text] [Related] [New Search]