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  • Title: Clinical ophthalmological tests for the diagnosis of keratoconjunctivitis sicca.
    Author: Prause JU.
    Journal: Clin Exp Rheumatol; 1989; 7(2):141-4. PubMed ID: 2736826.
    Abstract:
    According to the Copenhagen criteria for Sjögren's syndrome, the diagnosis of keratoconjunctivitis sicca requires the performance of 3 objective ocular tests of which 2 should give pathological results. The tests presently in use are: Break-up time, Schirmer-1-test and Rose-Bengal score. A list of clinical ophthalmological tests has been established in order to enable various SS-study groups to compare results. The list has 3 groups, each containing tests evaluating mainly one characteristic function of the lacrimal system: Tear production, tear quality and ocular surface condition. The tests of the list have been evaluated in 10 1 degree SS-patients and in 10 incipient SS patients. The diagnostic sensitivity and the accuracy of various combinations of the 3 tests have been evaluated. It is suggested that SS-study groups should select one of the marked (*) tests from each group on the list, and that KCS should be defined present, when 2 of the selected 3 tests show pathologically changed results. (table; see text).
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