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  • Title: Influence of calcitonin administration of serum calcium and inorganic phosphate level of the frog, Rana tigrina.
    Author: Srivastav AK, Rani L.
    Journal: Gen Comp Endocrinol; 1989 Apr; 74(1):14-7. PubMed ID: 2737450.
    Abstract:
    The effect of salmon calcitonin (0.25 MRC mU/g body wt) was investigated on the serum calcium and inorganic phosphate levels of the frog. Rana tigrina. The hormone evokes hypocalcemia (on Day 1 and Day 3) which is followed by a significant hypercalcemia on Day 10. Thereafter, the level of calcium decreases again on Day 15. Calcitonin induces hypophosphatemia (on Day 3 and Day 5). Thereafter, hyperphosphatemia is recorded on Day 10. Normal serum phosphate value is achieved by Day 15. The results obtained in R. tigrina have been discussed in relation to the increased calcium deposits in the paravertebral lime sacs and to the possible enhanced secretion of the parathyroid glands.
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