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  • Title: Allergy to local anesthetics: Reality or myth?
    Author: Malinovsky JM, Chiriac AM, Tacquard C, Mertes PM, Demoly P.
    Journal: Presse Med; 2016 Sep; 45(9):753-7. PubMed ID: 27378513.
    Abstract:
    The incidence of allergic reactions to local anesthetics is low. Most cases involve a psychogenic reaction rather than an allergic reaction. Additives and preservatives added to local anesthetics may cause allergic reactions. Vascular resorption of epinephrine-containing local anesthetics may produce cardiovascular signs similar to an allergic reaction. Diagnosis of allergy to local anesthetics must be established by skin testing and provocative challenge.
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