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  • Title: Canine antibody response to Lutzomyia longipalpis saliva in endemic area of visceral leishmaniasis.
    Author: Batista LF, Matta VL, Tomokane TY, Pacheco AD, Silveira FT, Rossi CN, Marcondes M, Laurenti MD.
    Journal: Rev Soc Bras Med Trop; 2016; 49(3):361-4. PubMed ID: 27384835.
    Abstract:
    INTRODUCTION: Canine exposure to Lutzomyia longipalpis bites and the potential of Leishmania infantum transmissibility for the vector were evaluated. METHODS: Immunoglobulin G (IgG) anti-Lu longipalpis saliva and -L. infantum, and blood parasite load were determined in dogs from endemic areas of visceral leishmaniasis. RESULTS: Blood parasitism was similar between symptomatic and asymptomatic dogs. IgG anti-L. infantum was higher in symptomatic dogs, but IgG anti-Lu. longipalpis saliva was mostly observed in higher titers in asymptomatic dogs, indicating vector preference for feeding on asymptomatic dogs. CONCLUSIONS: Our data suggest a pivotal role of asymptomatic dogs in L. infantum transmission in endemic areas.
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