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  • Title: Plasmonic nanohalo optical probes for highly sensitive imaging of survivin mRNA in living cells.
    Author: Qian GS, Kang B, Zhang ZL, Li XL, Zhao W, Xu JJ, Chen HY.
    Journal: Chem Commun (Camb); 2016 Sep 25; 52(74):11052-5. PubMed ID: 27412908.
    Abstract:
    A strategy is designed for sensitive detection of tumor biomarker survivin mRNA based on resonance Rayleigh scattering of a single AuNP nanohalo probe that couples large gold nanoparticles (L-AuNPs, 52 nm) with small AuNPs (S-AuNPs, 18 nm) through the affinity interaction between streptavidin and biotin. This core-satellite plasmon ruler is further applied to imaging survivin mRNA in living cells.
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