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  • Title: Development of protection and of self-cure in lambs infected daily with Ostertagia circumcincta.
    Author: Hong C, Michel JF, Lancaster MB.
    Journal: Vet Parasitol; 1989 May; 31(2):125-31. PubMed ID: 2741300.
    Abstract:
    Lambs were infected daily with 1000 Ostertagia circumcincta larvae. At intervals of 4 weeks groups of lambs were each challenged with a dose of 28,000 larvae, and their worm burdens compared with those of unchallenged controls. The measure of their ability to resist a challenge infection, which would have determined their degree of "protection", was obscured by the separate phenomenon of self-cure. Evidence suggested that the different manifestations of self-cure were determined by the state of resistance of the host and followed a set chronological sequence.
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