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  • Title: [The use of a tripeptide chromogenic substrate for simultaneous determination of 4 indices of kallikrein-kinin system].
    Author: Dotsenko VL, Iarovaia GA, Neshkova EA.
    Journal: Vopr Med Khim; 1989; 35(2):128-33. PubMed ID: 2741408.
    Abstract:
    Evaluation of the kallikrein-kinine system activity in blood plasma is of importance due to participation of the components of this system in regulation of blood plasma proteolysis. Using D-Pro-Phe-Arg-pNA as a substrate, a procedure for simultaneous estimation of four patterns of the kallikrein-kinine system activity was developed: I. maintenance of contact phase, 2. content of prekallikrein (1.49 un/ml in normal state), 3. activity of kallikrein (0.104 un/ml), 4. antikallikrein potential (0.700 IU/ml).
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