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  • Title: [Improved method of purification of L-lysine-alpha-oxidase from the fungus Trichoderma sp].
    Author: Iankevich NB, Laugalene NF, Vesa VS, Khaduev SKh, Smirnova IP.
    Journal: Vopr Med Khim; 1989; 35(2):84-6. PubMed ID: 2741419.
    Abstract:
    Relatively rapid procedure was developed for isolation and purification of the antitumor enzyme L-lysine alpha-oxidase. The procedure involved three steps instead of six or four steps described previously, with a yield of 64.4%. The homogenous preparation was obtained as shown by gel electrophoresis and ultracentrifugation. The antitumor activity of the enzyme both in vivo and in vitro is under investigation.
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