These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effect of noradrenaline on current- and voltage-clamped muscle cells of the guinea-pig vas deferens in normal Krebs solution.
    Author: Mimata T, Inomata H.
    Journal: Eur J Pharmacol; 1989 Apr 12; 163(1):181-5. PubMed ID: 2744092.
    Abstract:
    The ionic mechanism underlying the time-dependent alteration in the action potential configuration by noradrenaline (NA) was studied using vas deferens muscles voltage-clamped according to the double sucrose gap method. Early exposure to NA enhanced the inward Ca2+ current (ICa) by increasing conductance whereas late exposure diminished ICa by reducing the driving force. The degree of increase in the peak outward K+ current (IK') was higher with a greater enhancement of ICa by NA but the late outward K+ current (IK) was insensitive to NA.
    [Abstract] [Full Text] [Related] [New Search]