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  • Title: Periodic hyperammonemic encephalopathy associated with a ureterosigmoidostomy.
    Author: Cascino GD, Jensen JM, Nelson LA, Schutta HS.
    Journal: Mayo Clin Proc; 1989 Jun; 64(6):653-6. PubMed ID: 2747294.
    Abstract:
    Ureterosigmoidostomy, a urinary diversion procedure performed for treatment congenital urologic defects or bladder cancer, may be associated with hyperammonemia. A delayed periodic encephalopathy, characterized by dysarthria, ataxia, and coma, developed in a 44-year-old woman who had undergone this procedure. Hyperammonemia-associated neurotoxicity resolved after surgical revision of the ureterosigmoidostomy to a uretero-ileostomy. Therefore, a treatable episodic encephalopathy may occur in association with hyperammonemia in patients who have undergone ureterosigmoidostomy.
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